Characterization of a human thyroid microtissue model for testing thyroid disrupting chemicals

Characterization of a human thyroid microtissue model for testing thyroid disrupting chemicals

Perturbation of thyroid hormone (T4) synthesis is known to cause numerous developmental, metabolic, and cognitive disorders in humans. Due to species differences in sensitivity to chemical exposures, there is a need for human-based in vitro approaches that recapitulate thyroid cellular architecture...

Full description

Bibliographic Details
Main Authors: E. Rogers, E. K. Breathwaite, T. Nguyen-Jones, S. M. Anderson, J. J. Odanga, D. T. Parks, K. K. Wolf, T. Stone, P. Balbuena, J. Chen, S. C. Presnell, J. R. Weaver, E. L. LeCluyse
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Toxicology
Subjects:
thyroid
thyrocyte
thyroxine
thyroglobulin
microtissues
TDC
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2024.1408808/full

Internet

https://www.frontiersin.org/articles/10.3389/ftox.2024.1408808/full

Similar Items