Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood–Brain Barrier Model Derived from Hematopoietic Stem Cells

Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood–Brain Barrier Model Derived from Hematopoietic Stem Cells

We previously developed an in vitro model of the human blood–brain barrier (BBB) based on the use of endothelial cells derived from CD34<sup>+</sup>-hematopoietic stem cells and cultured with brain pericytes. The purpose of the present study was to provide information on the protein expr...

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Bibliographic Details
Main Authors: Marie-Pierre Dehouck, Masanori Tachikawa, Yutaro Hoshi, Kotaro Omori, Claude-Alain Maurage, Guillaume Strecker, Lucie Dehouck, Marie-Christine Boucau, Yasuo Uchida, Fabien Gosselet, Tetsuya Terasaki, Yannis Karamanos
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
blood–brain barrier
human in vitro models
human brain-like endothelial cells
brain microvessels
LC-MS/MS-based protein quantification
transporter
Online Access:https://www.mdpi.com/2073-4409/11/24/3963

Internet

https://www.mdpi.com/2073-4409/11/24/3963

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