Transcriptome-wide association study of circulating IgE levels identifies novel targets for asthma and allergic diseases

Transcriptome-wide association study of circulating IgE levels identifies novel targets for asthma and allergic diseases

Measurement of circulating immunoglobulin E (IgE) concentration is helpful for diagnosing and treating asthma and allergic diseases. Identifying gene expression signatures associated with IgE might elucidate novel pathways for IgE regulation. To this end, we performed a discovery transcriptome-wide...

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Bibliographic Details
Main Authors: Kathryn A. Recto, Tianxiao Huan, Dong Heon Lee, Gha Young Lee, Jessica Gereige, Chen Yao, Shih-Jen Hwang, Roby Joehanes, Rachel S. Kelly, Jessica Lasky-Su, George O’Connor, Daniel Levy
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
asthma
allergic diseases
IgE
immunoglobulin
gene expression
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1080071/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1080071/full

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