The role of tripartite motif-containing 28 in cancer progression and its therapeutic potentials

The role of tripartite motif-containing 28 in cancer progression and its therapeutic potentials

Tripartite motif-containing 28 (TRIM28) belongs to tripartite motif (TRIM) family. TRIM28 not only binds and degrades its downstream target, but also acts as a transcription co-factor to inhibit gene expression. More and more studies have shown that TRIM28 plays a vital role in tumor genesis and pro...

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Bibliographic Details
Main Authors: Yiqing Yang, Shiming Tan, Yaqian Han, Lisheng Huang, Ruiqian Yang, Zifan Hu, Yi Tao, Linda Oyang, Jinguan Lin, Qiu Peng, Xianjie Jiang, Xuemeng Xu, Longzheng Xia, Mingjing Peng, Nayiyuan Wu, Yanyan Tang, Xiaoling Li, Qianjin Liao, Yujuan Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
TRIM28
E3 ligase
proliferation
EMT
stemness sustainability
immune regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1100134/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1100134/full

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