Oocyte-specific gene knockdown by intronic artificial microRNAs driven by Zp3 transcription in mice

Conditional knockout technology is a powerful tool for investigating the spatiotemporal functions of target genes. However, generation of conditional knockout mice involves complicated breeding programs and considerable time. A recent study has shown that artificially designed microRNAs (amiRNAs), i...

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Bibliographic Details
Main Authors: Keisuke SASAKI, Saaya TAKAOKA, Yayoi OBATA
Format: Article
Language:English
Published: The Society for Reproduction and Development 2021-03-01
Series:The Journal of Reproduction and Development
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jrd/67/3/67_2020-146/_pdf/-char/en