Integrating metabolomics and network pharmacology to assess the effects of quercetin on lung inflammatory injury induced by human respiratory syncytial virus

Abstract Quercetin (QR) has significant anti-respiratory syncytial virus (RSV) effects. However, its therapeutic mechanism has not been thoroughly explored. In this study, a lung inflammatory injury model caused by RSV was established in mice. Untargeted lung tissue metabolomics was used to identify...

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Bibliographic Details
Main Authors: Ya-Lei Sun, Pei-Pei Zhao, Cheng-Bi Zhu, Ming-Chen Jiang, Xin-Min Li, Jia-Lei Tao, Chan-Chan Hu, Bin Yuan
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35272-8