Cyclic Stretch Promotes Cellular Reprogramming Process through Cytoskeletal‐Nuclear Mechano‐Coupling and Epigenetic Modification

Cyclic Stretch Promotes Cellular Reprogramming Process through Cytoskeletal‐Nuclear Mechano‐Coupling and Epigenetic Modification

Abstract Advancing the technologies for cellular reprogramming with high efficiency has significant impact on regenerative therapy, disease modeling, and drug discovery. Biophysical cues can tune the cell fate, yet the precise role of external physical forces during reprogramming remains elusive. He...

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Bibliographic Details
Main Authors: Sung‐Min Park, Jung‐Hwan Lee, Kwang Sung Ahn, Hye Won Shim, Ji‐Young Yoon, Jeongeun Hyun, Jun Hee Lee, Sunyoung Jang, Kyung Hyun Yoo, Yoon‐Kwan Jang, Tae‐Jin Kim, Hyun Kyu Kim, Man Ryul Lee, Jun‐Hyeog Jang, Hosup Shim, Hae‐Won Kim
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Advanced Science
Subjects:
cell reprogramming
epigenetic change
induced pluripotent stem cells
mechanotransduction
physical force
Online Access:https://doi.org/10.1002/advs.202303395

Internet

https://doi.org/10.1002/advs.202303395

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