Imaging asparaginyl endopeptidase (AEP) in the live brain as a biomarker for Alzheimer’s disease

Imaging asparaginyl endopeptidase (AEP) in the live brain as a biomarker for Alzheimer’s disease

Abstract Background Discovery of early-stage biomarkers is a long-sought goal of Alzheimer’s disease (AD) diagnosis. Age is the greatest risk factor for most AD and accumulating evidence suggests that age-dependent elevation of asparaginyl endopeptidase (AEP) in the brain may represent a new biologi...

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Bibliographic Details
Main Authors: Shan-Shan Wang, Zi-Kai Liu, Jing-Jing Liu, Qing Cheng, Yan-Xia Wang, Yan Liu, Wen-Wen Ni, Hong-Zhuan Chen, Mingke Song
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Nanobiotechnology
Subjects:
Alzheimer’s disease
Early diagnosis
Biomarker
Asparagine endopeptidase
Legumain
Live brain imaging
Online Access:https://doi.org/10.1186/s12951-021-00988-0

Internet

https://doi.org/10.1186/s12951-021-00988-0

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