The mechanistic immunosuppressive role of the tumour vasculature and potential nanoparticle-mediated therapeutic strategies

The tumour vasculature is well-established to display irregular structure and hierarchy that is conducive to promoting tumour growth and metastasis while maintaining immunosuppression. As tumours grow, their metabolic rate increases while their distance from blood vessels furthers, generating a hypo...

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Bibliographic Details
Main Authors: Zakaria Elias Ileiwat, Tanveer A. Tabish, Dmitry A. Zinovkin, Jale Yuzugulen, Nahid Arghiani, Md Zahidul I. Pranjol
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.976677/full