Tryptophan Breakdown in Patients with HCV Infection is Influenced by IL28B Polymorphism

Tryptophan Breakdown in Patients with HCV Infection is Influenced by IL28B Polymorphism

Until recently, the standard treatment of chronic hepatitis C virus (HCV) infection was a combination therapy with PEG-IFN-α plus ribavirin. Previous studies have proven that several markers predict the outcome of such therapy, e.g., pretreatment plasma levels of interferon inducible protein IP-10,...

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Bibliographic Details
Main Authors: Heinz Zoller, Annina Jenal, Albert F. Staettermayer, Sebastian Schroecksnadel, Peter Ferenci, Dietmar Fuchs
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Pharmaceuticals
Subjects:
IL28B polymorphism
tryptophan breakdown
indoleamine 2,3-dioxygenase
kynurenine to tryptophan ratio
neopterin
Online Access:http://www.mdpi.com/1424-8247/8/2/337

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http://www.mdpi.com/1424-8247/8/2/337

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