Autocrine/Paracrine Slit–Robo Signaling Controls Optic Lobe Development in Drosophila melanogaster

Cell segregation mechanisms play essential roles during the development of the central nervous system (CNS) to support its organization into distinct compartments. The Slit protein is a secreted signal, classically considered a paracrine repellent for axonal growth through Robo receptors. However, i...

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Bibliographic Details
Main Authors: M. Constanza González-Ramírez, Francisca Rojo-Cortés, Noemí Candia, Jorge Garay-Montecinos, Pablo Guzmán-Palma, Jorge M. Campusano, Carlos Oliva
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.874362/full