HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage

HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage

CD8+ T cells are key players during infection with the malaria parasite Plasmodium berghei ANKA (PbA). While they cannot provide protection against blood-stage parasites, they can cause immunopathology, thus leading to the severe manifestation of cerebral malaria. Hence, the tight control of CD8+ T...

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Bibliographic Details
Main Authors: Franziska Muscate, Nadine Stetter, Christoph Schramm, Julian Schulze zur Wiesch, Lidia Bosurgi, Thomas Jacobs
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
cerebral malaria
CD8 T cells
co-inhibitory receptors
HVEM
CD160
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02611/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02611/full

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