DEAD-Box RNA Helicase 21 (DDX21) Positively Regulates the Replication of Porcine Reproductive and Respiratory Syndrome Virus via Multiple Mechanisms

DEAD-Box RNA Helicase 21 (DDX21) Positively Regulates the Replication of Porcine Reproductive and Respiratory Syndrome Virus via Multiple Mechanisms

The porcine reproductive and respiratory syndrome virus (PRRSV) remains a persistent hazard in the global pig industry. DEAD (Glu-Asp-Ala-Glu) box helicase 21 (DDX21) is a member of the DDX family. In addition to its function of regulating cellular RNA metabolism, DDX21 also regulates innate immunit...

Full description

Bibliographic Details
Main Authors: Jia Li, Dang Wang, Puxian Fang, Yu Pang, Yanrong Zhou, Liurong Fang, Shaobo Xiao
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
porcine reproductive and respiratory syndrome virus (PRRSV)
DEAD-box helicases 21 (DDX21)
interferon
nonstructural protein 1β (nsp1β)
interaction
viral replication
Online Access:https://www.mdpi.com/1999-4915/14/3/467

Internet

https://www.mdpi.com/1999-4915/14/3/467

Similar Items