PTBP1 contributes to spermatogenesis through regulation of proliferation in spermatogonia

Polypyrimidine tract-binding protein 1 (PTBP1) is a highly conserved RNA-binding protein that is a well-known regulator of alternative splicing. Testicular tissue is one of the richest tissues with respect to the number of alternative splicing mRNA isoforms, but the molecular role(s) of PTBP1 in the...

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Bibliographic Details
Main Authors: Manami SENOO, Takashi TAKIJIRI, Nobuaki YOSHIDA, Manabu OZAWA, Masahito IKAWA
Format: Article
Language:English
Published: The Society for Reproduction and Development 2018-11-01
Series:The Journal of Reproduction and Development
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jrd/65/1/65_2018-109/_pdf/-char/en