Intermittent hypoxia induces time-dependent changes in the protein kinase B signaling pathway in the hippocampal CA1 region of the rat

Intermittent hypoxia induces time-dependent changes in the protein kinase B signaling pathway in the hippocampal CA1 region of the rat

Intermittent hypoxia (IH) during sleep induces temporally defined increases in apoptosis within vulnerable brain regions such as the hippocampal CA1 region in rats. Protein kinase B (AKT) has emerged as major signal transduction protein underlying inhibition of apoptosis and consequent increases in...

Full description

Bibliographic Details
Main Authors: Aviv Goldbart, Zixi (Jack) Cheng, Kenneth R Brittian, David Gozal
Format: Article
Language:English
Published: Elsevier 2003-12-01
Series:Neurobiology of Disease
Subjects:
Protein kinase B
Glycogen synthase kinase
Forkhead transcription factors
Sleep apnea
Hippocampus
Intermittent hypoxia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001608

Internet

http://www.sciencedirect.com/science/article/pii/S0969996103001608

Similar Items