An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial

An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial

Abstract Background Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the optimal dose of fluoroquinolones as part of the regimen has not been de...

Full description

Bibliographic Details
Main Authors: Tara C. Bouton, Patrick P. J. Phillips, Carole D. Mitnick, Charles A. Peloquin, Kathleen Eisenach, Ramonde F. Patientia, Leonid Lecca, Eduardo Gotuzzo, Neel R. Gandhi, Donna Butler, Andreas H. Diacon, Bruno Martel, Juan Santillan, Kathleen Robergeau Hunt, Dante Vargas, Florian von Groote-Bidlingmaier, Carlos Seas, Nancy Dianis, Antonio Moreno-Martinez, C. Robert Horsburgh
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Trials
Subjects:
Multidrug resistant tuberculosis
Optimized background regimen
Fluoroquinolones
Levofloxacin
Online Access:http://link.springer.com/article/10.1186/s13063-017-2292-x

Internet

http://link.springer.com/article/10.1186/s13063-017-2292-x

Similar Items