N-glycolyl chondroitin synthesis using metabolically engineered E. coli

N-glycolyl chondroitin synthesis using metabolically engineered E. coli

Abstract N-glycolyl chondroitin (Gc-CN) is a metabolite of N -glycolylneuraminic acid (Neu5Gc), a sialic acid that is commonly found in mammals, but not humans. Humans can incorporate exogenous Neu5Gc into their tissues from eating red meat. Neu5Gc cannot be biosynthesized by humans due to an evolut...

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Bibliographic Details
Main Authors: Adeola E. Awofiranye, Sultan N. Baytas, Ke Xia, Abinaya Badri, Wenqin He, Ajit Varki, Mattheos Koffas, Robert J. Linhardt
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:AMB Express
Subjects:
Sialic acid
Biotransformation
N-glycolyl chondroitin
Metabolite
N-glycolyl glucosamine
Online Access:http://link.springer.com/article/10.1186/s13568-020-01084-6

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http://link.springer.com/article/10.1186/s13568-020-01084-6

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