Microtubule-Stabilizing Drugs from Marine Sponges: Focus on Peloruside A and Zampanolide

Marine sponges are an excellent source of bioactive secondary metabolites with potential therapeutic value in the treatment of diseases. One group of compounds of particular interest is the microtubule-stabilizing agents, the most well-known compound of this group being paclitaxel (Taxol®), an anti-...

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Bibliographic Details
Main Authors: John H. Miller, A. Jonathan Singh, Peter T. Northcote
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/8/4/1059/