Effect of spironolactone and vitamin E on serum metabolic parameters and insulin resistance in patients with nonalcoholic fatty liver disease

Aim : The renin–angiotensin–aldosterone system has been implicated in the pathogenesis of insulin resistance and nonalcoholic fatty liver disease (NAFLD). The beneficial effect of spironolactone in a mouse model with diabetes and NAFLD has recently been reported. The main aim was assessment of the e...

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Main Authors: Stergios A Polyzos, Jannis Kountouras, Efthimia Zafeiriadou, Kalliopi Patsiaoura, Evangelia Katsiki, Georgia Deretzi, Christos Zavos, Georgios Tsarouchas, Pantelitsa Rakitzi, Aristidis Slavakis
Format: Article
Language:English
Published: SAGE Publications 2011-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320311402110