The Influence of Diabetic Peripheral Neuropathy on the Duration of Sciatic Nerve Block with 1.3% Liposomal Bupivacaine and 0.25% Bupivacaine Hydrochloride in a Mouse Model

The Influence of Diabetic Peripheral Neuropathy on the Duration of Sciatic Nerve Block with 1.3% Liposomal Bupivacaine and 0.25% Bupivacaine Hydrochloride in a Mouse Model

Little is known regarding the pharmacological properties of extended-release local anesthetics in the setting of diabetic peripheral neuropathy. We investigated and compared the duration of sciatic nerve block following administration of clinically relevant concentrations of liposomal bupivacaine (L...

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Bibliographic Details
Main Authors: Liljana Markova, Erika Cvetko, Chiedozie Kenneth Ugwoke, Simon Horvat, Nejc Umek, Tatjana Stopar Pintarič
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
peripheral nerve block
local anesthetics
liposomal bupivacaine
peripheral neuropathy
diabetes
Online Access:https://www.mdpi.com/1999-4923/14/9/1824

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https://www.mdpi.com/1999-4923/14/9/1824

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