High-dose pharmaceutical-grade biotin in patients with demyelinating neuropathies: a phase 2b open label, uncontrolled, pilot study

High-dose pharmaceutical-grade biotin in patients with demyelinating neuropathies: a phase 2b open label, uncontrolled, pilot study

Abstract Background We proposed to investigate high-dose pharmaceutical-grade biotin in a population of demyelinating neuropathies of different aetiologies, as a proof-of-concept. Methods Phase IIb open label, uncontrolled, single center, pilot study in 15 patients (three groups of five patients) wi...

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Bibliographic Details
Main Authors: Alain Créange, Emilie Hutin, Frédéric Sedel, Ludivine Le Vigouroux, Jean-Pascal Lefaucheur
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Neurology
Subjects:
Biotin
Peripheral neuropathies
Demyelination
Nerve excitability
Inflammatory neuropathy
CMT neuropathy
Online Access:https://doi.org/10.1186/s12883-023-03440-y

Internet

https://doi.org/10.1186/s12883-023-03440-y

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