An Optimised Monophasic Faecal Extraction Method for LC-MS Analysis and Its Application in Gastrointestinal Disease

An Optimised Monophasic Faecal Extraction Method for LC-MS Analysis and Its Application in Gastrointestinal Disease

Liquid chromatography coupled with mass spectrometry (LC-MS) metabolomic approaches are widely used to investigate underlying pathogenesis of gastrointestinal disease and mechanism of action of treatments. However, there is an unmet requirement to assess faecal metabolite extraction methods for larg...

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Bibliographic Details
Main Authors: Patricia E. Kelly, H Jene Ng, Gillian Farrell, Shona McKirdy, Richard K. Russell, Richard Hansen, Zahra Rattray, Konstantinos Gerasimidis, Nicholas J. W. Rattray
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Metabolites
Subjects:
mass spectrometry
metabolite extraction
inflammatory bowel disease
Crohn’s disease
coeliac disease
Online Access:https://www.mdpi.com/2218-1989/12/11/1110

Internet

https://www.mdpi.com/2218-1989/12/11/1110

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