Tumor cell-derived conditioned medium induced pro-tumoral phenotypes in macrophages through calcium-nuclear factor κB interaction

Abstract Background The malignant behaviors of lung cancers are affected by not only cancer cells but also many kinds of stromal cells in tumor microenvironment (TME), including macrophages. Macrophages have been proven to extensively influence tumor progression through several mechanisms, among whi...

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Bibliographic Details
Main Authors: Yuexin Zhang, Ziqi Zhang, Lei Chen, Xiuyue Zhang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-10431-8