Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats

Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats

End-stage age-related macular degeneration (AMD) and retinitis pigmentosa (RP) are two major retinal degenerative (RD) conditions that result in irreversible vision loss. Permanent eye damage can also occur in battlefields or due to accidents. This suggests there is an unmet need for developing effe...

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Bibliographic Details
Main Authors: Biju B. Thomas, Bin Lin, Juan Carlos Martinez-Camarillo, Danhong Zhu, Bryce T. McLelland, Gabriel Nistor, Hans S. Keirstead, Mark S. Humayun, Magdalene J. Seiler
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Neuroscience
Subjects:
retinal transplantation
retinal degeneration
human embryonic stem cells (hESCs)
tissue engineering
vision testing
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.752958/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.752958/full

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