Mutational characterization of HBV reverse transcriptase gene and the genotype-phenotype correlation of antiviral resistance among Chinese chronic hepatitis B patients

Mutational characterization of HBV reverse transcriptase gene and the genotype-phenotype correlation of antiviral resistance among Chinese chronic hepatitis B patients

ABSTRACTBackground and Aims: The drug resistance of hepatitis B virus (HBV) originates from mutations within HBV reverse transcriptase (RT) region during the prolonged antiviral therapy. So far, the characteristics of how these mutations distribute and evolve in the process of therapy have not been...

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Bibliographic Details
Main Authors: Ya Fu, Songhang Wu, Yuhai Hu, Tianbin Chen, Yongbin Zeng, Can Liu, Qishui Ou
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Hepatitis B virus
reverse transcriptase
resistant mutation
genotype
phenotype
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1835446

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https://www.tandfonline.com/doi/10.1080/22221751.2020.1835446

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