Effect of vinpocetine on embryonic heart rate in vitro

Effect of vinpocetine on embryonic heart rate in vitro

Vinpocetine is a readily available nutritional supplement claimed to improve memory and weight loss. However, it blocks the Ikr current essential for cardiac action potential repolarisation and Ikr inhibition can cause “torsade de pointes” arrhythmias and sudden death. Moreover, Ikr blockers have ex...

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Bibliographic Details
Main Authors: Helen Elizabeth Ritchie, Jaimie W. Polson, Andrea Xia, William Webster
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Toxicology
Subjects:
Vinpocetine
hERG
In vitro screen
Heart function
Birth defects
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X23000233

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http://www.sciencedirect.com/science/article/pii/S2666027X23000233

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