Identification of protein targets for the antidepressant effects of Kai-Xin-San in Chinese medicine using isobaric tags for relative and absolute quantitation

Identification of protein targets for the antidepressant effects of Kai-Xin-San in Chinese medicine using isobaric tags for relative and absolute quantitation

Kai-Xin-San consists of Ginseng Radix, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria at a ratio of 3:3:2:2. Kai-Xin-San has been widely used for the treatment of emotional disorders in China. However, no studies have identified the key proteins implicated in response to Kai-Xin-San treatment...

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Bibliographic Details
Main Authors: Xian-Zhe Dong, Dong-Xiao Wang, Tian-Yi Zhang, Xu Liu, Ping Liu, Yuan Hu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
brain-derived neurotrophic factor signal pathway; depression; isobaric tags for relative and absolute quantitation; Kai-Xin-San; neurogenesis; protein network; proteomics analysis; synaptic plasticity; traditional Chinese medicine
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=2;spage=302;epage=310;aulast=Dong

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=2;spage=302;epage=310;aulast=Dong

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