Quantitative input-output dynamics of a c-di-GMP signal transduction cascade in Vibrio cholerae.

Bacterial biofilms are multicellular communities that collectively overcome environmental threats and clinical treatments. To regulate the biofilm lifecycle, bacteria commonly transduce sensory information via the second messenger molecule cyclic diguanylate (c-di-GMP). Using experimental and modeli...

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Bibliographic Details
Main Authors: Andrew A Bridges, Jojo A Prentice, Chenyi Fei, Ned S Wingreen, Bonnie L Bassler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001585