Genomic landscape in acute myeloid leukemia and its implications in risk classification and targeted therapies

Abstract Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy in terms of clinical features, underlying pathogenesis and treatment outcomes. Recent advances in genomic techniques have unraveled the molecular complexity of AML leukemogenesis, which in turn have led to refinement of...

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Bibliographic Details
Main Authors: Hsin-An Hou, Hwei-Fang Tien
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-020-00674-7