Integrative transcriptomic and network pharmacology analysis reveals the neuroprotective role of BYHWD through enhancing autophagy by inhibiting Ctsb in intracerebral hemorrhage mice

Integrative transcriptomic and network pharmacology analysis reveals the neuroprotective role of BYHWD through enhancing autophagy by inhibiting Ctsb in intracerebral hemorrhage mice

Abstract Background In this study, we aimed to combine transcriptomic and network pharmacology to explore the crucial mRNAs and specific regulatory molecules of Buyang Huanwu Decoction (BYHWD) in intracerebral hemorrhage (ICH) treatment. Methods C57BL/6 mice were randomly divided into three groups:...

Full description

Bibliographic Details
Main Authors: Yiqing Cai, Zhe Yu, Xueping Yang, Weikang Luo, En Hu, Teng Li, Wenxin Zhu, Yang Wang, Tao Tang, Jiekun Luo
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Chinese Medicine
Subjects:
Intracerebral hemorrhage
Buyang Huanwu Decoction
Transcriptomic
Network pharmacology
Autophagy
Online Access:https://doi.org/10.1186/s13020-023-00852-3

Internet

https://doi.org/10.1186/s13020-023-00852-3

Similar Items