Vitamin D, FOXO3a, and Sirtuin1 in Hashimoto's Thyroiditis and Differentiated Thyroid Cancer
Background: Protective effects of vitamin D have been reported in autoimmune and malignant thyroid diseases, though little is known about the underlying mechanism. Sirtuin 1 histon deacethylase (SIRT1) links the vitamin D pathway with regulation of transcription factor FOXO3a, a key player in cell c...
Main Authors: | Natascha Roehlen, Claudia Doering, Martin-Leo Hansmann, Frank Gruenwald, Christian Vorlaender, Wolf Otto Bechstein, Katharina Holzer, Klaus Badenhoop, Marissa Penna-Martinez |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-09-01
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Series: | Frontiers in Endocrinology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fendo.2018.00527/full |
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