Vascularised cardiac spheroids-on-a-chip for testing the toxicity of therapeutics

Abstract Microfabricated organ-on-a-chips are rapidly becoming the gold standard for the testing of safety and efficacy of therapeutics. A broad range of designs has emerged, but recreating microvascularised tissue models remains difficult in many cases. This is particularly relevant to mimic the sy...

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Bibliographic Details
Main Authors: Stefania Di Cio, Emilie Marhuenda, Malcolm Haddrick, Julien E. Gautrot
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-53678-w