Suppression of transforming growth factor-β by mesenchymal stem-cells accelerates liver regeneration in liver fibrosis animal model

Suppression of transforming growth factor-β by mesenchymal stem-cells accelerates liver regeneration in liver fibrosis animal model

Introduction Liver fibrosis (LF) results from the unregulated chronic wound healing process in liver tissue. Transforming growth factor-beta (TGF-β) is the major contributing cytokine of LF promotion through activation of quiescent hepatic stellate cells (HSCs) into myofibroblasts (MFs) and increase...

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Bibliographic Details
Main Authors: Nur Anna C Sa’dyah, Agung Putra, Bayu Tirta Dirja, Nurul Hidayah, Salma Yasmine Azzahara, Risky Candra Satria Irawan
Format: Article
Language:English
Published: Faculty of Medicine Trisakti University 2021-02-01
Series:Universa Medicina
Subjects:
Liver fibrosis
mesenchymal stem cells
transforming growth factor-β
rats
Online Access:https://univmed.org/ejurnal/index.php/medicina/article/view/1079

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https://univmed.org/ejurnal/index.php/medicina/article/view/1079

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