The Phr1 Ubiquitin Ligase Promotes Injury-Induced Axon Self-Destruction
Axon degeneration is an evolutionarily conserved process that drives the loss of damaged axons and is an early event in many neurological disorders, so it is important to identify the molecular constituents of this poorly understood mechanism. Here, we demonstrate that the Phr1 E3 ubiquitin ligase i...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-05-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713001800 |