Altered O-GlcNAcylation and mitochondrial dysfunction, a molecular link between brain glucose dysregulation and sporadic Alzheimer’s disease

Altered O-GlcNAcylation and mitochondrial dysfunction, a molecular link between brain glucose dysregulation and sporadic Alzheimer’s disease

Alzheimer’s disease is a neurodegenerative disease that affected over 6.5 million people in the United States in 2021, with this number expected to double in the next 40 years without any sort of treatment. Due to its heterogeneity and complexity, the etiology of Alzheimer’s disease, especially spor...

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Bibliographic Details
Main Authors: Chia-Wei Huang, Nicholas C Rust, Hsueh-Fu Wu, Gerald W Hart
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease; amyloid beta; brain; glucose deficiency; glucose uptake; hypometabolism; mitochondrial dysfunction; neurodegenerative disease; neurons; o-glcnac; tau
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=4;spage=779;epage=783;aulast=Huang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=4;spage=779;epage=783;aulast=Huang

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