NF-κB, a culprit of both inflamm-ageing and declining immunity?

Abstract NF-κB is generally recognized as an important regulator of ageing, through its roles in cellular senescence and inflammatory pathways. Activated in virtually all cell-cell communication networks of the immune system, NF-κB is thought to affect age-related defects of both innate and adaptive...

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Bibliographic Details
Main Authors: Preeyaporn Songkiatisak, Shah Md Toufiqur Rahman, Mohammad Aqdas, Myong-Hee Sung
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-022-00277-w