LPCAT1 enhances castration resistant prostate cancer progression via increased mRNA synthesis and PAF production.

Our previously study shown that Lysophosphatidylcholine Acyltransferase1 (LPCAT1) is overexpressed in castration resistant prostate cancer (CRPC) relative to primary prostate cancer (PCa), and androgen controls its expression via the Wnt signaling pathway. While highly expressed in CRPC, the role of...

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Bibliographic Details
Main Authors: Chao Han, Guopeng Yu, Yuanshen Mao, Shangqing Song, Long Li, Lin Zhou, Zhong Wang, Yushan Liu, Minglun Li, Bin Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240801