SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53

Abstract Bladder cancer (BCa) is one of the most common malignancies worldwide. However, the lack of accurate and effective targeted drugs has become a major problem in current clinical treatment of BCa. Studies have demonstrated that squalene epoxidase (SQLE), as a key rate-limiting enzyme in chole...

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Bibliographic Details
Main Authors: Fan Zou, Wu Chen, Tianbao Song, Ji Xing, Yunlong Zhang, Kang Chen, Weimin Hu, Linzhi Li, Jinzhuo Ning, Chenglong Li, Weimin Yu, Fan Cheng
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-02997-5