Structural and functional distinctions of co-resident microglia and monocyte-derived macrophages after retinal degeneration

Abstract Background Both resident microglia and invading peripheral immune cells can respond to injury and degeneration in the central nervous system. However, after dead and dying neurons have been cleared and homeostasis is re-established, it is unknown whether resident immune cells fully resume n...

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Bibliographic Details
Main Authors: Kaitryn E. Ronning, Sarah J. Karlen, Marie E. Burns
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-022-02652-2