Renoprotective effects of extracellular fibroblast specific protein 1 via nuclear factor erythroid 2-related factor-mediated antioxidant activity

Abstract Podocyte expression of fibroblast specific protein 1 (FSP1) is observed in various types of human glomerulonephritis. Considering that FSP1 is secreted extracellularly and has been shown to have multiple biological effects on distant cells, we postulated that secreted FSP1 from podocytes mi...

Full description

Bibliographic Details
Main Authors: Naoki Takahashi, Seiji Yokoi, Hideki Kimura, Hironobu Naiki, Taiji Matsusaka, Yasuhiko Yamamoto, Kimihiko Nakatani, Kenji Kasuno, Masayuki Iwano
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49863-y