Preparation and Characterization of Celecoxib-Conjugated Polyethylenimine as a Potential Nanocarrier for Gene Delivery
The objective of the present investigation was to conjugate celecoxib as a cyclooxygenase-2 (COX-2) inhibitor onto polyethylenimine (PEI) in order to prepare nanoparticles for tissue targeting. Since celecoxib binds to COX-2 and this enzyme is over expressed in several pathological conditions includ...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Shiraz University of Medical Sciences
2018-03-01
|
| Series: | Trends in Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://tips.sums.ac.ir/article_42246_6e9aebdcfa921c81dcaa0917f4452086.pdf |