Formulation Development of Mirtazapine Liquisolid Compacts: Optimization Using Central Composite Design

Formulation Development of Mirtazapine Liquisolid Compacts: Optimization Using Central Composite Design

Mirtazapine is a tetracyclic anti-depressant with poor water solubility. The aim of this study was to improve the dissolution rate of mirtazapine by delivering the drug as a liquisolid compact. Central composite design (CCD) was employed for the preparation of mirtazapine liquisolid compacts. In thi...

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Bibliographic Details
Main Authors: Faiza Naureen, Yasar Shah, Sayyed Ibrahim Shah, Muhammad Abbas, Inayat Ur Rehman, Salar Muhammad, Hamdullah Hamdullah, Khang Wen Goh, Fazli Khuda, Amjad Khan, Siok Yee Chan, Mehwish Mushtaq, Long Chiau Ming
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
mirtazapine
green products
sustainable manufacturing
in vitro characterization
mental disease
dissolution enhancement
Online Access:https://www.mdpi.com/1420-3049/27/13/4005

Internet

https://www.mdpi.com/1420-3049/27/13/4005

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