Determination of the structure of the catabolic N-succinylornithine transaminase (AstC) from Escherichia coli.

Escherichia coli possesses two acyl ornithine aminotransferases, one catabolic (AstC) and the other anabolic (ArgD), that participate in L-arginine metabolism. Although only 58% identical, the enzymes have been shown to be functionally interchangeable. Here we have purified AstC and have obtained X-...

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Bibliographic Details
Main Authors: Janet Newman, Shane Seabrook, Regina Surjadi, Charlotte C Williams, Del Lucent, Matthew Wilding, Colin Scott, Thomas S Peat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590144?pdf=render