Hypofibrinogenemia is associated with a high degree of risk in infectious diseases: a post-hoc analysis of post-marketing surveillance of patients with disseminated intravascular coagulation treated with thrombomodulin alfa

Hypofibrinogenemia is associated with a high degree of risk in infectious diseases: a post-hoc analysis of post-marketing surveillance of patients with disseminated intravascular coagulation treated with thrombomodulin alfa

Abstract Background In patients with infectious diseases, disseminated intravascular coagulation (DIC) is often diagnosed without the fibrinogen value. The relationship between hypofibrinogenemia and outcomes of DIC in infectious diseases has thus remained unclear. Methods We analyzed 3204 patients...

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Bibliographic Details
Main Authors: Kazuo Kawasugi, Hideo Wada, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Seiji Madoiwa, Naoki Takezako, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Toshiaki Iba, Kohji Okamoto
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Thrombosis Journal
Subjects:
Disseminated intravascular coagulation
Hypofibrinogenemia
Thrombomodulin
Post-marketing surveillance
Infectious disease
Mortality
Online Access:https://doi.org/10.1186/s12959-021-00264-z

Internet

https://doi.org/10.1186/s12959-021-00264-z

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