Handling method affects measures of anxiety, but not chronic stress in mice

Abstract Studies in mice have shown that less aversive handling methods (e.g. tunnel or cup handling) can reduce behavioural measures of anxiety in comparison to picking mice up by their tail. Despite such evidence, tail handling continues to be used routinely. Besides resistance to change accustome...

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Bibliographic Details
Main Authors: Janja Novak, Ivana Jaric, Marianna Rosso, Reto Rufener, Chadi Touma, Hanno Würbel
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25090-9