Triazole-Estradiol Analogs Induce Apoptosis and Inhibit EGFR and Its Downstream Pathways in Triple Negative Breast Cancer
Triple negative breast cancer, TNBC, is a difficult disease to treat due to relapse and resistance to known therapies. Epidermal growth factor receptor (EGFR), a tyrosine kinase responsible for downstream signaling leading to cell growth and survival, is typically overexpressed in TNBC. Our previous...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Sprog: | English |
Udgivet: |
MDPI AG
2025-01-01
|
Serier: | Molecules |
Fag: | |
Online adgang: | https://www.mdpi.com/1420-3049/30/3/605 |