Triazole-Estradiol Analogs Induce Apoptosis and Inhibit EGFR and Its Downstream Pathways in Triple Negative Breast Cancer

Triple negative breast cancer, TNBC, is a difficult disease to treat due to relapse and resistance to known therapies. Epidermal growth factor receptor (EGFR), a tyrosine kinase responsible for downstream signaling leading to cell growth and survival, is typically overexpressed in TNBC. Our previous...

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Bibliografiske detaljer
Main Authors: Felix Acheampong, Trevor Ostlund, Emily Hedge, Jacqueline Laddusaw, Faez Alotaibi, Yaseen A. M. M. Elshaier, Fathi Halaweish
Format: Article
Sprog:English
Udgivet: MDPI AG 2025-01-01
Serier:Molecules
Fag:
Online adgang:https://www.mdpi.com/1420-3049/30/3/605