Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway

Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway

Procyanidins (PCs), which are organic antioxidants, suppress oxidative stress, exhibit anti−apoptotic properties, and chelate metal ions. The potential defense mechanism of PCs against cerebral ischemia/reperfusion injury (CIRI) was investigated in this study. Pre−administration for 7 days of a PC e...

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Bibliographic Details
Main Authors: Lei Chen, Jie Huang, Zi-Meng Yao, Xiao-Rong Sun, Xu-Hui Tong, Miao Hu, Ying Zhang, Shu-Ying Dong
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
procyanidins
cerebral
ischemia/reperfusion
ferroptosis
Nrf2/HO−1pathway
mice
Online Access:https://www.mdpi.com/1420-3049/28/8/3582

Internet

https://www.mdpi.com/1420-3049/28/8/3582

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