Autophagic Induction Greatly Enhances Leishmania major Intracellular Survival Compared to Leishmania amazonensis in CBA/j-Infected Macrophages

Autophagic Induction Greatly Enhances Leishmania major Intracellular Survival Compared to Leishmania amazonensis in CBA/j-Infected Macrophages

CBA mouse macrophages control Leishmania major infection yet are permissive to Leishmania amazonensis. Few studies have been conducted to assess the role played by autophagy in Leishmania infection. Therefore, we assessed whether the autophagic response of infected macrophages may account for the di...

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Bibliographic Details
Main Authors: Beatriz R. S. Dias, Carina S. de Souza, Niara de Jesus Almeida, José G. B. Lima, Kiyoshi F. Fukutani, Thiale B. S. dos Santos, Jaqueline França-Cost, Claudia I. Brodskyn, Juliana P. B. de Menezes, Maria I. Colombo, Patricia S. T. Veras
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Microbiology
Subjects:
Leishmania
macrophages
autophagy
LC3
parasitophorous vacuole
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01890/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01890/full

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