Azoxymethane-Induced Colorectal Cancer Mice Treated with a Polyphenol-Rich Apple Extract Show Less Neoplastic Lesions and Signs of Cachexia

Obesity is considered a risk factor for the development of colorectal cancer. In rodents, high-fat (HF) diets are able to increase the formation of azoxymethane (AOM)-induced polyps. Polyphenol-rich apple extracts have antioxidant and anti-inflammatory activities and may induce an amelioration of th...

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Bibliographic Details
Main Authors: Florencio Marzo, Fermin I. Milagro, Jaione Barrenetxe, María Teresa Díaz, J. Alfredo Martínez
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/10/4/863