Analytical quality-by-design approach for development and validation of HPLC method for the simultaneous estimation of omarigliptin, metformin, and ezetimibe: application to human plasma and dosage forms
Abstract A simple, selective, and sensitive RP-HPLC method was proposed for the simultaneous determination of two co-administered antidiabetic drugs (omarigliptin and metformin) with an anti-hyperlipidemic drug (ezetimibe) in a medicinally-recommended ratio of 2.5:50:1, respectively. The proposed pr...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-05-01
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Series: | BMC Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13065-023-00955-w |